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The restart will drop the connections being served by the flexvdi-gateway, so end users will be disconnected, but it does not affect the virtual machines.
Q: I get a System Error message when I start flexvdi-client on Windows.
The message says that "The program can start because ucrtbase.dll is missing from your computer", and looks like this in a Windows server.
To fix this, install the Visual C++ Redistributable for your OS. You have links to them at https://flexvdi.com/en/downloads